Situation: Francis, age 46 is admitted to the hospital with a diagnosis of Chronic Lymphocytic Leukemia. The treatment for patients with leukemia is bone marrow transplantation. Which statement about bone marrow transplantation is not correct?
A. The patient is under local anesthesia during the procedure.
B. The aspirated bone marrow is mixed with heparin.
C. The aspiration site is the posterior or anterior iliac crest.
D. The recipient receives cyclophosphamide (Cytoxan) for 4 consecutive days before the procedure.
Correct Answer: A. The patient is under local anesthesia during the procedure
Before the procedure, the patient is administered with drugs that would help to prevent infection and rejection of the transplanted cells such as antibiotics, cytotoxic, and corticosteroids. During the transplant, the patient is placed under general anesthesia.
Option B: An anticoagulant is often added to prevent cell clumping.
Option C: The iliac crest is preferred for safety reasons, because there are no major blood vessels or organs located close to this area.
Option D: Cyclophosphamide is given to prevent the incidence of graft-versus-host disease.