The risk of experiencing serotonin syndrome when SSRIs are given with monoamine oxidase inhibitors such as phenelzine (Nardil). Serotonin syndrome is best characterized in which of the following?
A. A productive cough and bradycardia
B. Hypotension and urinary retention
C. Muscle rigidity and high fever
D. Tea-colored urine and constipation
Correct Answer: C. Muscle rigidity and high fever
Serotonin syndrome is a potentially serious drug reaction causing the body to have excessive serotonin, a chemical produced by the nerve cells. Symptoms include fever, tachycardia, hypertension, agitation, muscle rigidity, tremor, sweating, dilated pupils, and diarrhea.