According to a standard staging classification of Hodgkin’s disease, which of the following criteria reflects stage III?
A. Involvement of lymph node regions or structures on both sides of the diaphragm
B. Involvement of two or more lymph node regions or structures
C. Involvement of single lymph node region or structure
D. Involvement of extralymphatic organs or tissues
Correct Answer: A. Involvement of lymph node regions or structures on both sides of the diaphragm
Option A: Hodgkin lymphoma is classified into stages to determine the state of the disease and where it has already spread. Stage III involves nodes on both sides of the diaphragm.
Option B: Stage II involves two or more lymph node regions.
Option C: Stage I only involves one lymph node region.
Option D: Stage IV involves extra lymphatic organs or tissues.