A client is receiving sulfasalazine (Azulfidine) for the treatment of ulcerative colitis. Which of the following assessment findings will concern the nurse most?
A. Drowsiness
B. Decreased urine output
C. Urine discoloration
D. Vomiting
Correct Answer: B. Decreased urine output
Sulfasalazine is used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in patients with ulcerative colitis. It is nephrotoxic, so a decrease in urine output is the most serious concern.
Options A, C, & D: These are also side effects but are less serious.